Friday, April 30, 2010

Risk Factors

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Some risk factors, such as age, sex and family history, can't be changed, whereas others, including weight, smoking and a poor diet, are under your control.

But having one or even several risk factors doesn't necessarily mean you'll develop cancer — most women with breast cancer have no known risk factors other than simply being women. In fact, being female is the single greatest risk factor for breast cancer. Although men can develop the disease, it's far more common in women.

Other factors that may make you more susceptible to breast cancer include:

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Age
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A personal history of breast cancer
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Genetic predisposition
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Radiation exposure
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Excess weight in upper part of body
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Late menopause
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First pregnancy at older age
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Birth control pills
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Mammographic breast density
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Precancerous breast changes (atypical hyperplasia, lobular carcinoma)

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Surgery

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Surgery can be an excision of the tumor with surrounding normal breast tissue (breast conservation) or removal of the whole breast (mastectomy). Clinical trials comparing mastectomy and breast conservation have shown that the two produce identical results.

If the lump is relatively small it is usually possible for the surgeon to remove it along with a small amount of surrounding normal tissue. This is called lumpectomy, wide local excision or breast-conserving surgery.

With a larger lump, this breast-conserving operation may not be possible because so much of the breast tissue would have been taken away that it would badly distort the breast.

Once the lump and surrounding tissue is removed it needs to be examined under the microscope. In some women, the surrounding tissue is abnormal and a further operation is necessary.

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